Department of Nephrology, Daping Hospital | China
Chen Kehong, MD, PhD, is a Professor of Nephrology and Deputy Director of the Department of Nephrology at Daping Hospital, Army Medical University, where he also serves as a doctoral supervisor. He received his medical and doctoral training in nephrology and internal medicine and has developed an academic career combining clinical leadership with translational research. His professional experience includes directing regional quality control initiatives in peritoneal dialysis and leading collaborative dialysis alliances in Southwest China. Actively involved in national and regional academic societies, he contributes to discipline development, guideline promotion, and talent cultivation in nephrology. His research interests focus on acute kidney injury to chronic kidney disease transition, diabetic kidney disease, renal inflammation, mitochondrial dysfunction, autophagy/mitophagy, epigenetic regulation, and blood purification therapies, with sustained funding from the National Natural Science Foundation of China and regional innovation programs. He has published extensively in high-impact journals, contributing influential findings to renal pathophysiology and immunometabolism. His achievements have been recognized through multiple provincial science and technology awards and talent honors. Overall, Professor Chen is regarded as a clinician-scientist whose integrated leadership, research excellence, and commitment to advancing kidney medicine continue to shape nephrology practice and innovation in China.
Featured Publications
Dou, Q., Tong, H., Chen, J., Yi, X., Bai, L., He, J., & Chen, K. (2025). IER3 drives the transition from sepsis-associated acute kidney injury to chronic kidney disease by suppressing the mitochondrial translocation of PRDX5. Cellular and Molecular Life Sciences, Advance online publication.
Han, J., Zhang, S., Hou, Y., Wang, Y., Zhang, Z., Yang, J., Xu, Y., Peng, Z., Yin, H., & Chen, K. et al. (2025). A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement. Immunity, Advance online publication.
Yu, F., Meng, Y., Wang, X., Chen, J., He, J., Yi, X., He, Y., & Chen, K. (2025). Protein lactylation of citrate synthase promotes the AKI–CKD transition by activating the NLRP3 inflammasome. Cell Reports, Advance online publication.
Chen, J., Wang, W., Yu, F., Wang, X., He, Y., & Chen, K. (2025). Urinary DcR2/Cr level predicts renal outcomes in patients with diabetic kidney disease. Journal of Clinical & Translational Endocrinology, Advance online publication.
Yu, F., Chen, J., Wang, X., Hou, S., Li, H., Yao, Y., He, Y., & Chen, K. (2025). Metabolic reprogramming of peritoneal mesothelial cells in peritoneal dialysis-associated fibrosis: Therapeutic targets and strategies. Cell Communication and Signaling, Advance online publication.