Assoc. Prof. Dr. Fakhrossadat Mohammadi | Interdisciplinary Research | Research Excellence Award
Institute for Advanced Studies in Basic Sciences (IASBS) | Iran
Fakhrossadat Mohammadi is an accomplished researcher and scholar specializing in protein chemistry, nanobiotechnology, and bioinorganic interactions. She holds advanced degrees in chemistry and molecular sciences and has extensive experience in spectroscopic, computational, and biochemical methods for studying protein-ligand interactions. Over the past decade, she has contributed significantly to understanding the molecular mechanisms of amyloid fibril formation and inhibition, exploring the interactions of natural and synthetic curcuminoids, flavonoids, and metal complexes with proteins such as α-lactalbumin, lysozyme, and serum albumins. Her work combines in vitro, in silico, and analytical approaches to uncover the structural, functional, and antiamyloidogenic properties of bioactive compounds. Mohammadi’s research extends to nanoparticle-protein interactions, including silver, gold, and superparamagnetic nanoparticles, and their effects on protein stability and biological activity. She has published extensively in high-impact journals, including International Journal of Biological Macromolecules, Biochemical and Biophysical Research Communications, Royal Society Open Science, and Langmuir, and her studies are recognized for advancing therapeutic strategies against amyloid-related diseases. Her research interests include protein misfolding, enzyme inhibition, bio-nanomaterials, molecular docking, and spectroscopic characterization. Mohammadi’s work is noted for its methodological rigor and potential translational applications, contributing to the fields of biochemistry, medicinal chemistry, and nanobiotechnology.
Featured Publications
Analysis of binding interaction of curcumin and diacetylcurcumin with human and bovine serum albumin using fluorescence and circular dichroism spectroscopy
– F Mohammadi, AK Bordbar, A Divsalar, K Mohammadi, AA Saboury, The Protein Journal 28 (3), 189-196, 2009
Analysis of binding interaction of genistein and kaempferol with bovine α-lactalbumin
– F Mohammadi, M Moeeni, Journal of Functional Foods 12, 458-467, 2015
Interaction of curcumin and diacetylcurcumin with the lipocalin member β-lactoglobulin
– F Mohammadi, AK Bordbar, A Divsalar, K Mohammadi, AA Saboury, The Protein Journal 28 (3), 117-123, 2009
Study on the interactions of trans-resveratrol and curcumin with bovine α-lactalbumin by spectroscopic analysis and molecular docking
– F Mohammadi, M Moeeni, Materials Science and Engineering: C 50, 358-366, 2015
Inhibition of amyloid fibrillation of hen egg-white lysozyme by the natural and synthetic curcuminoids
– F Mohammadi, A Mahmudian, M Moeeni, L Hassani, RSC Advances 6 (28), 23148-23160, 2016